I’ve been using the BIOMA Digestive & Gut Repair Probiotics for a couple of months now. I am very happy with the results as my system, which was never regulated, is now on a schedule and I feel great! Thank you for this product.
The "CONSTIPATION TRAP"
95% of Americans Are Butyrate-Deficient and Struggle to Poop Regularly[1]
Here's How To Fix It In 2 Days[2]
As you age, your gut's butyrate production declines—it's the fuel your intestinal cells need to function.[3] Without it, you're trapped in a cycle where constipation causes more constipation.
Bioma breaks that cycle in 2 days with an advanced 5-in-1 gut barrier repair formula. [2]
- Poop every morning without straining*
- Feel confident in fitted clothes*
- Enjoy meals without fear*
- Stop planning your day around bathrooms*
- Go to bed feeling light*
- 100% Money-Back Guarantee
- Free Shipping
- Cancel Anytime
Delayed-Release Capsules
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Non-GMO
Gluten-Free
Manufactured in USA
BENEFITS OF OUR INGREDIENTS ARE RESEARCHED BY
Choose Your BIOMA Package And Put An End To The Constipation Trap
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Try It Out SAVE 40%
1-Month Supply
Perfect for trying out
$53.99per bottle
$89.99
- 30 servings ($1.79/day)
- See initial results in 2 weeks*
- 1 bottle delivered
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1-Month Supply
Perfect for trying out
$71.99per bottle
$89.99
- 30 servings ($2.39/day)
- See initial results in 2 weeks*
- 1 bottle delivered
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3-Month Supply
Build healthy habits
$49.49per bottle
$89.99
- 90 servings ($1.64/day)
- Establish daily regularity
- 3 bottles delivered
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3-Month Supply
Build healthy habits
$62.99per bottle
$89.99
- 90 servings ($2.09/day)
- Establish daily regularity
- 3 bottles delivered
Best Value SAVE 50%
6-Month Supply
Full gut repair cycle
$44.99per bottle
$89.99
- 180 servings ($1.49/day)
- Complete digestive freedom
- 6 bottles delivered
Best Value Save 35%
6-Month Supply
Full gut repair cycle
$58.49per bottle
$89.99
- 180 servings ($1.94/day)
- Complete digestive freedom
- 6 bottles delivered
Plans renews automatically till cancelled
-
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Gluten-Free | Vegan
Organic Mushrooms
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Delayed-Release Capsules
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Manufactured in USA
Join 47,000+ Bioma's Customers Who Went From Backed Up To Regular, Smooth Poops in 2 Days
I've tried EVERYTHING... fiber, probiotics, laxatives and nothing worked long term. Bioma gave me relief in 3 days and I've been regular ever since... I actually look forward to my mornings now!
No more painful straining. No more planning my route and day around where the next clean bathroom is... The first thing that actually worked for me. Thank you!!!
I was skeptical about the 48-72 hours claim but all I can say is WOW.. I mean by the end of day 2 I felt lighter, less bloated and actually pooped without forcing it. My pants fit better too...
95% of Americans are Butyrate-Deficient
Butyrate is your colon’s #1 fuel source. A short-chain fatty acid produced when healthy gut bacteria digest fiber.
Think of it as “superfuel” for your intestinal cells.
Here's what it does:
✓ Powers your colon cells - Provides 60-70% of their energy needs
✓ Seals your gut lining - Repairs damaged gut barrier and maintains tight junctions
✓ Drives muscle contractions - Moves waste through your digestive tract
✓ Controls inflammation - Keeps your immune system balanced
Without enough butyrate, your gut barrier weakens, inflammation increases, and digestion slows to a crawl.
That's why you are constipated and can't poop regularly.
Your body doesn’t make butyrate, your gut bacteria do. But modern life has wiped out the bacteria responsible for producing it.
The 3 Main culprits:
1. Low-fibre diets
Butyrate is produced when gut bacteria ferment fiber. Most Americans eat less than half the recommended fiber intake, starving the bacteria that make butyrate.
2. Antibiotics
Even a single course of antibiotics can wipe out butyrate-producing bacteria for months. Many never fully recover.
3. Chronic stress
Stress hormones kill beneficial bacteria and promote harmful bacteria that don’t produce butyrate.
The result is that 95% of Americans can't produce enough butyrate to maintain a healthy gut barrier.
“The Constipation Trap” is a vicious cycle where constipation literally causes more constipation.
Here's how it works:
And it gets worse with age. Butyrate production by your gut bacteria declines up to 50% as you get older.
You’re trapped because:
- Your damaged gut can’t produce butyrate
- Without butyrate, your gut can’t heal
- Your constipation prevents the bacterial activity needed to make butyrate
- The cycle repeats itself
Butyrate is your colon's #1 fuel source. A short-chain fatty acid produced when healthy gut bacteria digest fiber.
Think of it as 'superfuel' for your intestinal cells.
Bioma doesn’t just treat symptoms, it repairs the foundation. You break free from the “Constipation Trap” because your gut can finally produce butyrate again.
What Happens When You Fix Your Gut The Scientifically Proven Way
Highest Standards of Quality, Powerhouse Ingredients, All Backed By Science
Initial Relief
Days 1-3 (48-72 Hours)
What's happening: Gut barrier repair begins, inflammation decreases, motility improves
What you'll notice:
- Less bloating after meals
- Reduced cramping
- Easier bowel movements starting
Regularity Restored
Weeks 1-2
What's happening: Good bacteria multiply, probiotics colonize, enzymes optimize digestion
What you'll notice:
- Consistent daily bowel movements
- No more straining or forcing
- Feel lighter and more energized
Full System Reset
Months 1-2
What's happening: Gut barrier fully repaired, microbiome rebalanced, natural butyrate production restored
What you'll notice:
- Complete regularity (no surprises)
- Clothes fit noticeably better
- Eat wider variety of foods
- Better mood and sleep quality
- Zero bathroom anxiety
Deep Optimization
Months 3-4
What's happening: Microbiome diversity peaks, immune strengthening, peak digestive efficiency, inflammation markers drop significantly
What you'll notice:
- Zero bloating, even after big meals
- Better stress resilience
- Clearer, more radiant skin
- Fewer food sensitivities
- Feel 'bulletproof' digestively
Peak Performance & Protection
Months 5-6+
What's happening: Self-sustaining microbiome, lasting gut barrier strength, metabolic health improvements, anti-aging benefits from butyrate, peak immune function
What you'll notice:
- Effortless digestion is your new normal
- Sustained weight management
- Enhanced mental clarity and focus
- Overall vitality boost
- Fewer sick days
- Forgot what constipation feels like
- Friends notice you look healthier
Why Choose a 6-Month Supply?
Why Choose a 6-Month Supply?
Months 1-2
Fix the problem
Months 3-4
Optimize system
Months 5-6
Lock in transformation
"This is more than just a supplement, it's a lifestyle change."
What’s Inside Your Bioma Bottle
Highest Standards of Quality, Powerhouse Ingredients, All Backed By Science
Ingredients
-
Prebiotics
Fructo-Oligosaccharides (FOS) nourish good bacteria like Bifidobacteria and Lactobacilli. These strains of good bacteria restore balance in your microbiome to ease bloating, improve regularity, and support lasting gut health. -
Probiotics
10 Billion CFU of clinically proven Howaru® Restore strains help rebuild a healthy gut flora, improve digestion, and maintain regularity – even when diet, travel, or stress throw you off balance. -
Postbiotics
Tributyrin from CoreBiome® helps strengthen the gut lining for better nutrient absorption, reduced inflammation, and protection against toxins. Laboratory research shows it begins supporting barrier function within just 48 hours [1], and benefits may appear within as little as 7 days.* -
Digestive Enzymes
A natural blend of Bromelain and Papain helps break down heavy meals more efficiently. This relieves bloating, gas, and lets you enjoy food without discomfort. -
Mushroom Beta - Glucans
Our mushroom complex feeds the bacteria that build your gut barrier, helps convert food into clean energy, and triggers immune cells to wake up and do their job. This means less irritation, better resilience, and more balanced immune responses.
How to take
Take 2 capsules daily with a glass of water, preferably with a meal.
For best results:
- Take consistently at the same time each day
- Continue for at least 2-3 months (best 6+) to allow your gut to fully reset
- Safe for long-term daily use
Start in the morning to establish a routine, or take with your largest meal for optimal digestion support.
Why Delayed-Release Capsules Matter
Most probiotics fail because 95% of bacteria die in your stomach acid before reaching your colon[13], where you actually need them.
Bioma delayed-release capsules solve this:
✓ Protect ingredients from stomach acid
✓ Deliver probiotics alive to your colon where they can colonize
✓ Release butyrate exactly where your gut barrier needs it
✓ Maximize effectiveness of every ingredient
That’s why Bioma works when generic probiotics fail, your gut actually receives what’s on the label.
What Makes Our 5-in-1 Formula Different
Most probiotics only add bacteria, but if your gut barrier is damaged, it’s like planting flowers in front of a burning house.
Bioma’s 5-in-1 system breaks the Constipation Trap by repairing the foundation first:
🛡️ SEAL - CoreBiome® butyrate repairs your damaged gut barrier in 2 days
🌱 FEED - Prebiotic fiber feeds beneficial bacteria
🦠 RESTORE - 4 clinically-studied probiotic strains replenish good bacteria
⚙️ DIGEST - Enzymes break down food to prevent fermentation
🛡️ STRENGTHEN - Mushroom beta-glucans reduce inflammation
Unlike generic probiotics that just add bacteria, Bioma addresses the root cause, your damaged gut barrier and butyrate deficiency, so your gut can heal and produce butyrate naturally again.
Bioma vs. Everything Else You've Tried
What You Need
Seals Gut Barrier
Yes
No
No
No
Clinical-Grade Postbiotic
Yes
No
No
No
Feeds Good Bacteria
Yes
Partial
No
No
Survives Stomach Acid
Yes
Yes
No
Yes
10 Billion CFU Probiotics
Yes
No
Varies
No
Digestive Enzymes
Yes
No
No
No
Immune Support
Yes
No
Limited
No
Works in 48 hours
Yes
No
No
Yes
Addresses Root Cause
Yes
No
No
No
Safe Long-Term
Yes
Yes
Yes
No
No Dependency
Yes
Yes
Yes
No
Choose Your BIOMA Package And Put An End To The Constipation Trap
Cancel Anytime
Free Shipping for All Subscribers
100% Money-Back Guarantee
Try It Out SAVE 40%
1-Month Supply
Perfect for trying out
$53.99per bottle
$89.99
- 30 servings ($1.79/day)
- See initial results in 2 weeks*
- 1 bottle delivered
Try It Out Save 20%
1-Month Supply
Perfect for trying out
$71.99per bottle
$89.99
- 30 servings ($2.39/day)
- See initial results in 2 weeks*
- 1 bottle delivered
Most Popular SAVE 45%
3-Month Supply
Build healthy habits
$49.49per bottle
$89.99
- 90 servings ($1.64/day)
- Establish daily regularity
- 3 bottles delivered
Most Popular Save 30%
3-Month Supply
Build healthy habits
$62.99per bottle
$89.99
- 90 servings ($2.09/day)
- Establish daily regularity
- 3 bottles delivered
Best Value SAVE 50%
6-Month Supply
Full gut repair cycle
$44.99per bottle
$89.99
- 180 servings ($1.49/day)
- Complete digestive freedom
- 6 bottles delivered
Best Value Save 35%
6-Month Supply
Full gut repair cycle
$58.49per bottle
$89.99
- 180 servings ($1.94/day)
- Complete digestive freedom
- 6 bottles delivered
Plans renews automatically till cancelled
FDA & GMP Certified
Third-Party Tested
Secure Checkout
Gluten-Free | Vegan
Organic Mushrooms
Dark Glass Bottles for Product Quality
Delayed-Release Capsules
100% Natural & Non-GMO
Manufactured in USA
100% Money-Back Guarantee
We're so confident BIOMA Digestive and Gut Repair Probiotics will transform your digestive health and end constipation trap, that we offer a complete money-back guarantee.
If you don't see meaningful improvement in your constipation within 14 days, simply contact us for a full refund. No questions asked.
100% Money-Back Guarantee
Free Shipping
Cancel Anytime
Our Customers Talk About Bioma
Customer Reviews
Overall rating: 4.6 / 5 from 370 reviews.
My gut feels healthier, my energy is better, and I don’t feel sluggish after meals anymore. Such an easy addition to my routine.
My gut feels so much better, and I’ve noticed I’m not holding onto as much bloat. I just feel slimmer overall.
Some days my schedule is all over the place and my digestion hates me. This stuff has been a lifesaver!
Honestly, this works fast and like a charm. I’ve been using it regularly and it actually keeps everything regulated. None of that harsh laxative stuff. Just smooth, normal digestion, if you know what I mean.
I pack this on every single trip without fail. It became a travel essential for me, and I even share it with my husband. We both notice the difference when we take it.
These digestive probiotics quietly do their job. My digestion feels more consistent and my tummy feels less bloated without me having to think about it.
I never travel without these digestive and gut repair probiotics. They’re part of my daily routine and make such a difference for digestion and keeping my tummy flat.
I’ve struggled with leaky gut symptoms for a while, and this probiotic has really helped. My digestion feels calmer and my stomach is much less sensitive.
Simple, effective, and easy on my stomach. Less heaviness after eating and better digestion overall. Solid product.
Really impressed with how fast this worked. The heaviness in my stomach improved quickly, and my digestion felt regular again within 24 hours
This probiotic really helped reduce my bloating. My tummy feels flatter and more comfortable, especially after meals.
My bloating is down and I feel clean inside. Bioma is actually working.
I’m not usually one to leave reviews, but Bioma honestly surprised me. After a month, my gut feels totally reset — no bloating, steady energy, and I don’t even need my morning coffee to get going. This stuff actually works!
One week in and I’m not looking five months pregnant after lunch. Praise the LORD.
been on this for 3 weeks. no flare-ups. no running to the bathroom. no crying after pasta. it’s working. that’s all i need to say.
There’s nothing glamorous about chronic gut problems. But this has been one of the few things I’ve added that’s made a real difference… I’m not “cured” but definitely way better.
Honestly shocked. no more bloating after meals, I’ve gone down a size in jeans because I’m no longer gassy!!
I’m 38 and only now feel like my gut is now working the way it should. I have IBD. Now everything is way smoother, less discomfort, and I’ve got more energy through the day
This fixed my constipation… finally… i didn’t realize how much irregular BMs were affecting my mood…. digestion feels normal again.
I’ve struggled with bloating for years, literally bloated 24/7. but after a couple weeks on Bioma, my tummy feels flatter and lighter. Looove it
I’ve experienced little to no improvement with my gas and bloating.
The order was easy to make and arrived quickly. After more than six months use, I am satisfied Bioma is the best.
Very Effective Probiotic.
I think the product is working well. Thank you.
It smells terrible. I need to cancel any further orders. Capsules are very large and difficult to swallow. Please cancel all future orders. Thank you. Geri Miller-Riedel
I want to cancel my subscription.
Initially, I believe the product seemed to work. I'm still taking it, so we will see going forward. However, I have been trying to reach your company to update the delivery address but have received no response, so I may not reorder from you.
Experienced change for the better immediately. No negative effects.
As I’m into the beginning of my second bottle I’m feeling a little less bloated some of the time.
Not sure yet.
Certainly helped heal my IBS!!
Since I have been taking Bioma Digestive and Gut Repair, the bloating has gone down and I do not have it like I did. I take it in the mornings with other meds with no reactions between them. My stomach feels much better, it doesn’t hurt like in the past. If you have gut health problems I highly recommend purchasing Bioma Digestive and Gut Repair.
I have had bloating issues for three years. They are becoming severe. I have lost 10 pounds (185 to 175) because I feel too bloated to eat anything. In spite of the weight loss I’ve gone up two inches on my waist (36 to 38). I’ve had a colonoscopy and a endoscopy and the gastrointestinologist could find nothing. I also follow the fodmaps diet. My hope is that the Bioma Probiotic will reverse any bad bacteria in my gut. I’ve only been on this for two weeks. So far all remains the same. I’m being patient.
great
Very happy so far. Less bloat, more regularity
I like that I can eat out without paying for it all night. Still can’t go too crazy, but my gut tolerates fun food way better now.
lost 2 pounds the first week it was abit nuts
no runs since starting this
ok I HAVE to say this – my mood got better?? :D like less irritable, less tired after meals. I started for bloat but the brain fog lifting is actually my fav part.
Gut Repair Formula, Backed by Science
FDA & GMP Certified
Third-Party Tested
Secure Checkout
Gluten-Free | Vegan
Organic Mushrooms
Dark Glass Bottles for Product Quality
Delayed-Release Capsules
100% Natural & Non-GMO
Manufactured in USA
Frequently Asked Questions
Get answers to common questions about BIOMA
Most customers notice less bloating and easier bowel movements within the first 48-72 hours. Full gut repair and consistent regularity typically occurs within 2-4 weeks as your gut barrier heals and microbiome rebalances.
Yes. Bioma is formulated with natural, clinically-tested ingredients and is designed for daily, long-term use. It's manufactured in FDA-registered, GMP-certified facilities and is third-party tested for purity and potency. Unlike laxatives, Bioma doesn't create dependency.
Traditional probiotics only add bacteria, most of which die in stomach acid. Bioma uses delayed-release capsules AND repairs your gut barrier FIRST with CoreBiome® postbiotic. This creates a healthy environment where probiotics can actually survive and thrive.
Many of our customers have IBS-C (IBS with constipation), chronic constipation, or other digestive issues. Bioma addresses the root cause, gut barrier dysfunction, which underlies many digestive problems. However, we recommend consulting your doctor if you have severe conditions
We offer a 100% money-back guarantee. If you don't see meaningful improvement within 14 days, simply contact our customer service team for a full refund. No questions asked. We take all the risk so you don't have to.
100% Money-Back Guarantee
Free Shipping
Cancel Anytime
References
[
1
]
- Quagliani D, Felt-Gunderson P. Closing America's Fiber Intake Gap: Communication Strategies From a Food and Fiber Summit. Am J Lifestyle Med. 2016 Jul 7;11(1):80-85.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6124841/
[
2
]
- Vance A, Raut S, Grier-Welch A, Alamdari N, Sharafi M. A Novel Combination of Pre-, Pro-, and Postbiotics Demonstrates Protective Effects on Intestinal Permeability in an In Vitro Gut Barrier Model. eBioMedicine. 2024;106:105247.
https://www.sciencedirect.com/science/article/pii/S2475299123208707
[
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]
- Kirschner SK, Engelen MPKJ, Haas P, et al. Short-chain fatty acid kinetics and concentrations are higher after inulin supplementation in young and older adults: a randomized trial. Am J Clin Nutr. 2025 Jun;121(6):1224-1235.
https://pubmed.ncbi.nlm.nih.gov/40274191/
[
4
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- Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol. 2011 Mar 28;17(12):1519-28.
https://pubmed.ncbi.nlm.nih.gov/21472114/
[
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- Peng L, Li ZR, Green RS, Holzman IR, Lin J. Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers. J Nutr. 2009 Sep;139(9):1619-25.
https://pubmed.ncbi.nlm.nih.gov/19625695/
[
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- Willing BP, Russell SL, Finlay BB. Shifting the balance: antibiotic effects on host-microbiota mutualism. Nat Rev Microbiol. 2011 Apr;9(4):233-43.
https://pubmed.ncbi.nlm.nih.gov/21358670/
[
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- Karl JP, Hatch AM, Arcidiacono SM, Pearce SC, Pantoja-Feliciano IG, Doherty LA, Soares JW. Effects of Psychological, Environmental and Physical Stressors on the Gut Microbiota. Front Microbiol. 2018 Sep 11;9:2013.
https://pubmed.ncbi.nlm.nih.gov/30258412/
[
8
]
- Shepherd SJ, Parker FC, Muir JG, Gibson PR. Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence. Clin Gastroenterol Hepatol. 2008 Jul;6(7):765-71.
https://pubmed.ncbi.nlm.nih.gov/18456565/
[
9
]
- Dodoo CC, Wang J, Basit AW, Stapleton P, Gaisford S. Targeted delivery of probiotics to enhance gastrointestinal stability and intestinal colonisation. Int J Pharm. 2017 Jul 15;530(1-2):224-229.
https://discovery.ucl.ac.uk/id/eprint/1568933/1/Gaisford_IJP%20probiotics%20R1.pdf
[
10
]
- Xing JH, Soffer EE. Adverse effects of laxatives. Dis Colon Rectum. 2001 Aug;44(8):1201-9.
https://pubmed.ncbi.nlm.nih.gov/11535863/
