95% of Your “Calm Hormone” Is Made In Your Gut[1], Not Your Brain
Chronic stress damages the vagus nerve — your gut-brain connection[2]. So even though your gut makes 95% of serotonin it can’t reach your brain, leaving you stuck in stress mode.
Bioma Probiotics’ 3-in-1 Anti-Stress formula restores it in 4-6 weeks.
- Wake up calm instead of on edge before your eyes open*
- Stop snapping at small things that used to set you off*
- Fall asleep in 20 minutes, not 2 hours with your mind finally quiet*
- Get through your day without that constant knot in your stomach*
- Feel like yourself again, calm steady, in control*
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THE GUT-BRAIN DISCONNECT
77% of Americans Experience Stress Symptoms Regularly[3],
And it starts in the gut.
Modern life creates a perfect storm that damages both the vagus nerve and the bacteria that produce calming neurotransmitters:
Chronic Stress Overload
77% of Americans report experiencing regular stress symptoms[3]. Chronic stress releases cortisol, which damages gut lining and reduces vagal tone.[7]
Dying Gut Bacteria
Modern diet, antibiotics, and stress kill beneficial bacteria that produce short-chain fatty acids, the compounds that trigger serotonin production[8].
Inflammation Blocks Signals
Chronic inflammation physically blocks the vagus nerve's ability to transmit signals[2], like static on a phone line.
The data backs this up: Mental health diagnoses jumped from 31% to 45% in just 4 years, with stress-related issues among the top reported[9].
It’s a vicious cycle you can’t escape without addressing the root cause:
- Stress damages your vagus nerve
- Your gut can’t send calm signals
- Your brain stays in stress mode
- More stress damages your gut further
- The cycle repeats.
You’re trapped because:
- Gut bacteria that make calming hormones are depleted
- Vagus nerve can’t transmit signals effectively
- Brain never gets the “all clear” to relax
- Every day without fixing it, the trap gets tighter
What Happens When You Restore Your Gut-Brain Connection From The Ground Up
Here’s exactly what to expect when you start Bioma Anti-Stress Probiotics.
Days 1-3 (48-72 Hours)
What's happening: Gut barrier repair begins, inflammation decreases, probiotic colonization starts
What you'll notice:
- Your stomach feels calmer, less reactive to stress*
- You take naturally deeper breaths*
- That tight chest feeling starts easing*
Weeks 1-2
What's happening: Good bacteria multiply, GABA production begins, vagus nerve signaling improves
What you'll notice:
- Wake up without that heavy dread feeling*
- Small annoyances don’t trigger you the same way*
- Racing thoughts at bedtime start to slow down*
- Less bloating and digestive discomfort*
Months 1-2
What's happening: Gut barrier fully repaired, serotonin production optimized, microbiome rebalance, stress hormone regulation improves
What you'll notice:
- Fall asleep faster without mental spiraling*
- You don’t rehearse conversation in your head anymore*
- Digestion noticeably better, less stress-triggered gut issues*
- Your baseline shifts from tense to steady*
- People comment you seem calmer, more present*
Months 3-4
What's happening: Vagus nerve tone strengthens, HPA axis rebalancing, peak gut-brain communication, stress resilience peaks
What you'll notice:
- Stressful situations don’t make you spiral*
- You bounce back from stress instead of ruminating*
- Consistent calm energy throughout the day*
- Better sleep quality, wake up rested*
- Mental clarity and focus improve*
Months 5-6+
What's happening: Self-sustaining microbiome, lasting vagus nerve strength, optimized neurotransmitter production, long-term stress resilience
What you'll notice:
- Calm becomes your baseline, not tension*
- Your gut and brain work together seamlessly*
- You feel like yourself again, steady and centered*
- Handle unexpected stress with ease*
- Overall mood and vitality boost*
- Friends say you look more relaxed and healthy*
- Forgot what constant worry feels like*
Why Choose a 6-Month Supply?
Months 1-2
Fix the problem
Months 3-4
Optimize system
Months 5-6
Lock in transformation
“This isn’t just a supplement, it’s getting my life back. I didn’t realize how much stress was running me until I felt what calm actually feels like.”
What’s Inside Your Bioma Probiotics Anti-Stress Bottle
Clinically-proven strains. Pharmaceutical-grade quality. Complete transparency.
Ingredients
-
Every ingredient is backed by published research on gut-brain axis function:
-
Prebiotic - Chicory Root Inulin (250mg)
Research shows that gut bacteria ferment inulin to produce short-chain fatty acids (SCFAs), which stimulate serotonin production from enterochromaffin cells in the gut[8].
-
Probiotics - Vagus Nerve Blend (12 Billion CFU)
Three strains with published clinical research on gut-brain communication:
Lactiplantibacillus plantarum Lp815[13]:
✓ Clinically proven to produce GABA in humans
✓ Statistically significant improvement in stress makers at 4 weeks
✓ 68% improved emotional balance at 6 weeks
✓ Increased urinary GABA and 5-HIAA (serotonin metabolite) levels
Lacticaseibacillus rhamnosus HN001[14]:
✓ Supports healthy gut microbiome during stress
✓ Helps maintain emotional wellness
✓ Promotes calm and balance mood
Bifidobacterium longum BI-05[15]:
✓ Survives stomach acid and adheres to intestinal lining
✓ Supports digestive health and regular bowel movements
✓ Part of the B. longum species associated with gut-brain health -
Postbiotic - TriBiom™ Tributyrin (350mg)
Research shows tributyrin supports[12]:
✓ Gut barrier integrity (tight junction function)
✓ Anti-inflammatory effects via vagus nerve signaling
✓ Reduced intestinal inflammation that can interfere with vagal transmission
How to take
Dosage: Take 2 capsules once daily with a full glass of water, ideally in the morning before breakfast.
For best results:
✓ Take at the same time every day (gut microbiome thrives on consistency)
✓ Give it at least 4 weeks
✓ Continue for 2-4 months minimum
Important: Results build over time as your gut microbiome rebalances. This is not a quick-fix supplement, but a biological restoration process.
Storage: Keep in a cool, dry place. No refrigeration required, strains are shelf-stable and delayed-release capsules protect potency.
Why Delayed-Release Capsules Matter
The challenge with probiotics: Stomach acid kills most bacteria. Studies show that standard probiotic capsules lose 60-90% of bacterial viability during gastric transit.[17]
Bioma’s solution:
✓ Acid-resistant delayed-release capsules protect bacteria through the acidic stomach environment
✓ pH-dependent release ensures capsules dissolve in the intestines where bacteria need to colonize
✓ Significantly higher survival rate compared to standard capsules, ensuring more live bacteria reach the gut.
✓ Delayed-release technology is considered best practice in probiotic formulation for clinical efficacy
Without delayed-release, you’re paying for bacteria that die before reaching the gut-brain axis.
What Makes Our 3-in-1 Formula Different
Most stress supplements only mask symptoms, and generic probiotics aren't tested for stress response and emotional balance. But if your gut-brain communication is broken, temporary relief won't solve the problem.
Bioma Probiotics’ 3-in-1 system restores calm from the ground up by fixing the root cause:
🛡️ PREPARE - TriBiom™ tributyrin repairs your gut barrier so you can absorb what your brain needs
🦠 RESTORE - 3 clinically-proven strains help produce GABA and serotonin where 95% is made (your gut)
🌱 FEED - Prebiotic inulin keeps good bacteria thriving and serotonin production flowing
Bioma Probiotics target the root cause: disrupted gut-brain communication. Not symptoms, or temporary relief. But biological restoration backed by published clinical trials.
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Bioma Probiotics Anti-Stress vs. Everything Else You’ve Tried
Choose Your BIOMA Probiotics Package And Restore Your Gut-Brain Connection
1 bottle supply
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- 30 servings ($1.79/day)
- Perfect for trying out
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1 bottle supply
Perfect for trying out
- 30 servings ($2.39/day)
- Perfect for trying out
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- 90 servings ($1.64/day)
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- 90 servings ($2.09/day)
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6 bottles supply
Full gut repair cycle
- 180 servings ($1.49/day)
- Full Anti- Stress cycle
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6 bottles supply
Full gut repair cycle
- 180 servings ($1.94/day)
- Full Anti- Stress cycle
- 6 bottles delivered
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100% Money-Back Guarantee
If you don’t notice any improvements within 14 days: less feelings of occasional unease, calmer mood, or better sleep quality, simply contact us for a full refund.
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Anti-Stress Formula, Backed by Science.
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Frequently Asked Questions
Get answers to common questions about BIOMA
Most customers notice less bloating and easier bowel movements within the first 48-72 hours. Full gut repair and consistent regularity typically occurs within 2-4 weeks as your gut barrier heals and microbiome rebalances.
Yes. Bioma is formulated with natural, clinically-tested ingredients and is designed for daily, long-term use. It's manufactured in FDA-registered, GMP-certified facilities and is third-party tested for purity and potency. Unlike laxatives, Bioma doesn't create dependency.
Traditional probiotics only add bacteria, most of which die in stomach acid. Bioma uses delayed-release capsules AND repairs your gut barrier FIRST with CoreBiome® postbiotic. This creates a healthy environment where probiotics can actually survive and thrive.
Many of our customers have IBS-C (IBS with constipation), chronic constipation, or other digestive issues. Bioma addresses the root cause, gut barrier dysfunction, which underlies many digestive problems. However, we recommend consulting your doctor if you have severe conditions
We offer a 100% money-back guarantee. If you don't see meaningful improvement within 14 days, simply contact our customer service team for a full refund. No questions asked. We take all the risk so you don't have to.
